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망막하 주사 또는 추출용 중공형 마이크로니들 및 망막하 주사기
专利权人:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION; YONSEI UNIVERSITY
发明人:
JUNG, Hyung Il,정형일,LEE, Chang Yeol,이창열,LEE, Kwang,LEE, Sung Ho,이성호,YOU, Yong Sung,유용성
申请号:
KRKR2013/002971
公开号:
WO2013/154336A1
申请日:
2013.04.09
申请国别(地区):
WO
年份:
2013
代理人:
摘要:
The present invention relates to a method for manufacturing a hollow microneedle for subretinal injection or extraction, wherein the method comprises the steps of: (a) applying a viscous material solution onto the surface of a substrate (b) placing a frame in contact with the viscous material solution (c) manufacturing a solid microneedle by lifting the substrate, the frame, or the substrate and the frame so as to space apart the contacted frame and the substrate (d) imparting a curved shape to the solid microneedle during step (c) or after completing step (c) (e) depositing a metal onto the solid microneedle to which the curved shape has been imparting (f) plating the solid microneedle, onto which the metal has been deposited, with a metal (g) bevel-cutting the tip of the solid microneedle that has been plated with the metal and (h) removing the solid microneedle, to thereby achieve a curved hollow microneedle. The microneedle for subretinal injection or extraction is made of metal, thereby providing the strength and force for penetrating the sclera and retina. Due to the length and the angle of curvature, the microneedle for subretinal injection or extraction of the present invention can reach a suitable subretinal site, such as the midperiphery at which optic nerves are accumulated, and thus the present invention is effective for delivering a drug and can enhance the effectiveness of the drug.La présente invention concerne un procédé de fabrication dune microaiguille creuse pour injection ou extraction sous-rétinienne, le procédé comprenant les étapes suivantes : (a) application dune solution de matériau visqueux sur la surface dun substrat (b) placement dun cadre en contact avec la solution de matériau visqueux (c) fabrication dune microaiguille pleine en soulevant le substrat, le cadre, ou le substrat et le cadre de façon à séparer le cadre et le substrat qui étaient en contact (d) attribution dune forme incurvée à la microaiguille pleine pendant létape (c)
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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