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Acylthiols et leurs compositions utilisés en tant qu'agents anti-HIV et en tant qu'agents anti-retroviraux
专利权人:
THE GOV. OF USA; AS REPRESENTED BY THE SECRETARY;DEPT. OF HEALTH AND HUMAN SERVICES; NATIONAL INSTITUTES OF HEALTH
发明人:
申请号:
EP02756732.0
公开号:
EP1425262B1
申请日:
2002.07.25
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Certain thiol and acylthiol compounds inhibit retrovirus growth by attacking the highly conserved zinc finger regions of essential viral proteins. These compounds, compositions containing them, and methods of using them to treat retroviral infections such as HIV are described. These compounds are also useful for preparation of vaccines comprised of inactivated retroviruses such as HIV, prevention of the transmission of such retroviruses, and detection of retroviral proteins.
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