Topical, vitamin D, oral supplement compositions useful in treating oral inflammation comprising vitamin D in an aqueous-free emulsion containing a trans-oral mucosal absorption facilitator, where said emulsion forms a mucoadhesive coating in the presence of saliva； wherein saliva dissolution of the mucoadhesive gel releases vitamin D and the trans-oral mucosal, absorption facilitator； effecting: vitamin D passive diffusion； regulating in vivo availability and immune response of vitamin D； and maintaining adequate levels of circulating vitamin D while minimizing the risk of hypercalcemia.
