Matthew Pollard;Anthony G. Doyle;Stephen Tran;Adam William Clarke
发明人:
Adam William Clarke,Anthony G. Doyle,Matthew Pollard,Stephen Tran
申请号:
US13810474
公开号:
US09127057B2
申请日:
2011.07.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure provides an isolated or recombinant IL-23-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain specifically binds to IL-23 but does not significantly bind to an IL-12p40 subunit and does not significantly bind to an IL-23p19 subunit when they are not components of IL-23. The present disclosure also provides uses of the IL-23-binding protein.