CLARKE, ADAM WILLIAM,DOYLE, ANTHONY G.,POLLARD, MATTHEW,TRAN, STEPHEN
申请号:
CA2805653
公开号:
CA2805653A1
申请日:
2011.07.20
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present disclosure provides an isolated or recombinant IL-23-binding protein comprising an antigen binding domain of an antibody, wherein the antigen binding domain specifically binds to IL-23 but does not significantly bind to an IL-12p40 subunit and does not significantly bind to an IL-23p19 subunit when they are not components of IL-23. The present disclosure also provides uses of the IL-23-binding protein.