BAYER SCHERING PHARMA AKTIENGESELLSCHAFT;THE GENERAL HOSPITAL CORPORATION;BAYER AKTIENGESELLSCHAFT;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;THE BROAD INSTITUTE INC.
The invention provides the triacyl compounds, wherein R1, R2, R3, R4 and R5 are the triacyl compounds defined in the invention, the preparation methods of these compounds, the intermediate compounds for preparing these compounds, the pharmaceutical components and mixtures containing these compounds, and the use This compound, as a single preparation or combined with other active ingredients, when preparing pharmaceutical ingredients for the treatment or prevention of diseases, especially high-risk disorders, presents a general formula (I) for providing cyanuric compound compounds, wherein R1, R2, R3,R4 and R5 are as defined herein methods of preparing said compounds intermediate compounds useful for preparing said compounds pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases in particular of hyperproliferative disorders as aLa presente invención proporciona compuestos de triazolona de la fórmula general en donde R1, R2, R3, R4 y R5 son como se definen en la presente, métodos de preparación de dichos compuestos, compuestos intermedios útiles para preparar dichos compuestos, composiciones farmacéuticas y combinaciones que comprenden dichos compuestos y el uso de dichos compuestos para preparar composiciones farmacéuticas para el tratamiento o la profilaxis de enfermedades, en particular de trastornos hiperproliferativos, como un único agente o en combinación con otros ingredientes activosThe present invention provides triazolone compounds compounds of general formula (I) : in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyp
