This Invention describes and claims a series of carboxamidas N - phenyl - bipirrolidina replaced in formula (i). (i) where R1, R2 m, N and P are as defined earlier in this document.More specifically, the compounds of this Invention are modulators of h3 receptors and are therefore useful as pharmaceutical agents, especially in the Prevention and / or treatment of a variety of diseases Modulated by h3 receptors associated with the disease, including Central nervous system.In addition, the present Invention also describes methods for the preparation of N - phenyl - carboxamidas bipirrolidina replaced and Intermediates for this purpose.ESTA INVENCION DESCRIBE Y REINVINDICA UNA SERIE DE CARBOXAMIDAS N- FENIL-BIPIRROLIDINA SUSTITUIDAS EN FORMULA (I). (I) DONE R1, R2 M,N Y P SON COMO SE DEFINIO ANTERIORMENTE EN ESTE DOCUMENTO. MAS ESPECIFICAMENTE, LOS COMPUESTOS DE ESTA INVENCION SON MODULADORES DE LOS RECEPTORES H3 Y POR LO TANTO, SON UTILES COMO AGENTES FARMACEUTICOS, ESPECIALMENTE EN EL TRATAMIENTO Y/O PREVENCION DE UNA VARIEDAD DE ENFERMEDADES MODULADAS POR LOS RECEPTORES H3, INCLUYENDO ENFERMEDADES ASOCIADAS CON EL SISTEMA NERVIOSO CENTRAL.ADEMAS, LA PRESENTE INVENCION TAMBIEN DESCRIBE METODOS PARA LA PREPARACION DE CARBOXAMIDAS N-FENIL-BIPIRROLIDINA SUSTITUIDAS E INTERMEDIOS PARA ELLO.
