Pharmaceutical formulation having reverse thermal gelation properties for local delivery of nanoparticles

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专利权人:

Exchange Imaging Technologies GmbH

发明人:

Greb, Wolfgang

申请号：

AU2015356991

公开号：

AU2015356991A1

申请日:

2015.12.06

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention refers to a pharmaceutical formulation for injection comprising fluorescent nanoparticles as in vivo diagnostics. The present invention relates to an injectable pharmaceutical formulation for human medicine and/or veterinary use, comprising 17% to 20% per weight of poloxamer 407 and 3% - 15% per weight of poloxamer 188, 0.10 nM to 10.0 μΜ fluorescent nanoparticles and water or an aqueous buffer, wherein the pharmaceutical formulation is liquid at 4°C - 32°C and forms a gel at about 37°C, their use as an

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