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Analogs of thalidomide as potential angiogenesis inhibitors
专利权人:
William D. Figg
发明人:
William D. Figg,Kurt Eger,Uwe Teubert,Michael Weiss,Michael Guetschow,Thomas Hecker,Sunna Hauschildt
申请号:
US11880404
公开号:
US08716315B2
申请日:
2007.07.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A number of thalidomide metabolites having superior anti-angiogenic properties have now been isolated and identified. In addition, thalidomide analogs that mimic the effects of the isolated and identified active thalidomide metabolites, and variations of such thalidomide analogs, have been developed. Such thalidomide analog compounds show enhanced potency in the inhibition of undesirable angiogenesis without the undesirable effects of administration of thalidomide.
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