ALESSANDRO SANNINO,BARRY JOSEPH HAND,CHRISTIAN DEMITRI,EYAL S. RON,YISHAI ZOHAR
申请号:
BR112013031209
公开号:
BR112013031209A2
申请日:
2012.06.07
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.