Tim Bowden,Kristoffer Bergman,Thomas Engstrand,Lennart Soderberg
申请号：
US15053645
公开号：
US09962451B2
申请日:
2016.02.25
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A composition for treating or preventing inflammatory-related conditions includes as an active principle a carrier which exhibits a plurality of a scavenger structure capable of mitigating the activity of a mediator of inflammatory-related conditions. The scavenger structure includes a nucleophilic center complying with the formula X1(—R″—)(—R′)mHn where: a) X1 is a single-bonded heteroatom selected amongst N, O and S and exhibits a free electron pair b) m is 0 or 1 and n is 1 or 2 c) —R″— is a bivalent organic group providing attachment to the carrier via one of its free valences and to X1 at the other free valence and d) R′— is a monovalent organic group attached to the X1 via its free valence. A method for treating or preventing inflammatory-related conditions in an individual suffering from such conditions includes: providing the composition and contacting the mediator within or separate from the individual.
