AGENT THERAPEUTIQUE AMELIORANT LES PROPRIETES DE LA PEAU COMPRENANT UN DERIVE DU MORPHINANE OU UN DE SES SELS D'ADDITION ACIDES PHARMACOLOGIQUEMENT ACCEPTABLES EN TANT QU'INGREDIENT ACTIF
The object of this invention is to provide a novel medicineuseful for therapy to improve (reduce) the skin propertiessuch as skin drying, skin roughening and the skin darkeninginvolved in hyperkeratosis (thickened keratin layer) via askin moisture retaining effect against the decline of theskin functions brought about by various causes. Thisinvention provides a skin property-improving therapeuticagent comprising a compound having a specific morphinanskeleton typified by a compound 1 represented by thefollowing formula (II) or any of its pharmacologicallypermissible acid addition salts as an active ingredient.[Chemical formula 1](see formula 1)