PROBLEM TO BE SOLVED: To provide a technique for improving the stability of a halogenated isoquinoline derivative with respect to light in an aqueous composition.SOLUTION: The present invention provides a pharmaceutical formulation for prevention or treatment of at least one disease selected from ocular hypertension and glaucoma, wherein an aqueous composition containing ripasudil or a salt thereof or their solvates is stored in a package that blocks a ray with a wavelength of 300 to 335 nm.SELECTED DRAWING: None【課題】ハロゲン化イソキノリン誘導体の、水性組成物中での光に対する安定性を改善する技術を提供すること。【解決手段】リパスジル若しくはその塩又はそれらの溶媒和物を含有する水性組成物が、波長300~335nmの光線を遮断する包装体に収容されてなる、高眼圧症及び緑内障から選ばれる1種以上の疾患の予防又は治療用の医薬製剤。【選択図】なし