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Therapeutic and delivery methods of prostaglandin EP4 agonists
专利权人:
Inc.;Allergan
发明人:
Im, Wha Bin,Donde, Yariv,Holoboski, Mark,Old, David W.,Kedzie, Karen M.,Gil, Daniel W.,Donello, John E.,Burk, Robert M.,Gac, Todd S.
申请号:
AU2005299473
公开号:
AU2005299473B2
申请日:
2005.10.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
A compound comprising a prodrug of a prostaglandin EP agonist, wherein said prodrug is an ester, ether, or amide of a carbohydrate; or said prodrug is an ester, ether, or amide of an amino acid is disclosed herein. Maintenance of the colonic mucosal barrier by method comprising administering a therapeutically effective amount of a prostaglandin EP agonist to a colon of a mammal is also disclosed herein. Dosage forms, medicaments, and compositions, related thereto are also disclosed.
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