Tissue fixation systems and associated methods and kits are described herein. An example embodiment of a tissue fixation system includes a locking screw and a tissue manipulator. The locking screw has a locking screw lengthwise axis and a locking screw main body that defines a locking screw exterior thread that extends in a first direction around the locking screw lengthwise axis and a locking screw interior thread that extends in a second direction around the locking screw lengthwise axis that is the same as the first direction. The tissue manipulator has a tissue manipulator lengthwise axis, a shaft, and a coil. The shaft has a shaft main body that defines a shaft exterior thread that extends in a third direction around the tissue manipulator lengthwise axis that is the same as the first direction. The coil extends from the shaft in a fourth direction around the tissue manipulator lengthwise axis that is different than the first direction.
