LIU, SHU-HUI S-H,.劉,HO, WEI-HSIEN W-H,.胡,STROP, PAVEL P,.施特羅普,DORYWALSKA, MAGDALENA, GRAZYNA MG,.多里沃爾斯卡,RAJPAL, ARVIND A,.拉吉帕爾,SHELTON, DAVID, LOUIS DL,.謝爾頓,TRAN, THOMAS-TOAN TT,.德蘭
申请号：
HK15102314.8
公开号：
HK1201851A
申请日:
2015.03.06
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The present invention provides antibodies that specifically bind to trophoblast cell-surface antigen-2 (Trop-2). The invention further provides antibody conjugates comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and Trop-2 antibody conjugates for the treatment of a condition associated with Trop-2 expression (e.g., cancer), such as colon, esophageal, gastric, head and neck, lung, ovarian, or pancreatic cancer.
