Bone formation is helped, the membrane for bone organization playback induction whose extraction after the bone forming is easy is offered.Including with the calcium phosphate layer which is put on collagen layer and the said collagen layer which consist of the collagen or the thermal denaturation collagen which is provided in both sides or one side of the parent hydration film and the said film of the polyester or the polyamide which becomes the backing material the membrane and the production method for bone organization playback induction of becoming.骨形成を助け、骨形成後の摘出が容易な骨・組織再生誘導用メンブレンを提供する。基材となるポリエステルまたはポリアミドの親水化フィルムと、該フィルムの両面または片面に設けたコラーゲンまたは熱変性コラーゲンからなるコラーゲン層と、該コラーゲン層の上に被せたリン酸カルシウム層とを含んでなる骨・組織再生誘導用メンブレンとその製造方法。
