Anti CD25 FC gamma receptor bispecific antibodies for tumor specific cell depletion

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专利权人:

Cancer Research Technology Limited

发明人:

Quezada, Sergio,Peggs, Karl,Vargas, Fred

申请号：

AU2017247880

公开号：

AU2017247880A1

申请日:

2017.03.17

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present disclosure relates to a method of treating a solid tumour, wherein said method involves the use of an antibody to CD25. In particular, the antibody to CD25 is optimized for depletion of regulatory T cells (Treg) within tumours. The present invention also provides novel anti-CD25 antibodies and their combination with other anti-cancer drugs, such as immune checkpoint inhibitors, compounds that target cancer antigens or the inhibitory Fc receptor FcyRllb (CD32b).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/