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STABLE PHARMACEUTICAL FORMULATION
专利权人:
CELLTRION INC.
发明人:
Joon Won LEE,Won Yong HAN,Su Jung KIM,Jun Seok OH,So Young KIM,Kwang Woo KIM,Yeon Kyeong SHIN
申请号:
US16345453
公开号:
US20190248871A1
申请日:
2017.10.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed is a stable pharmaceutical formulation, comprising a fusion protein in which the extracellular ligand-binding domain of a human p75 tumor necrosis factor receptor is fused to the Fc domain of human IgG and a succinate buffering agent, without comprising a stabilizer. The stable pharmaceutical formulation enables the long-term storage of the TNFR-Fc fusion protein formulation and can exhibit superior storage stability without the need for demanding storage conditions, and is a simple formulation because no stabilizer is comprised therein and is thus more economical than other stabilizer-comprising formulations.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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