FIELD: medicine.SUBSTANCE: invention relates to medical equipment, namely to systems of diagnostic visualisation with ultrasound. Method lies in introduction of contrast-enhancing preparation into monitored tissue, obtaining, during period of preparation action, support 3D CEUS volume and information of monitoring and picture in real time of monitored tissue, formation of multiplanar picture reconstruction of (MPR) with contrast enhancement (CEUS), for one of obtained pictures in real time, representation of obtained picture in real time, showing instrument within required part, and corresponding picture MPR CEUS for interventional navigation, after expiration of the period of contrast enhancement action. In the second version of method picture MPR CEUS is spatially registered with corresponding obtained images in real time. In the third version of method implementation maximal intensity projection (MIP) is formed as function of, at least, obtained 3D CEUS volume and information of monitoring and pictures in real time and is represented with instrument within required part. System contains ultrasound scanner, made with possibility of introduction of contrast -enhancing preparation into monitored tissue, obtaining support 3D CEUS volume and information of monitoring and formation of corresponding multiplanar picture reconstruction (MPR) with contrast enhancement (CEUS), and representation device, connected with it for representation of obtained pictures in real time.EFFECT: application of the invention makes it possible to increase accuracy of aiming in interventional procedures without necessity to change course of work or switch to other module of visualisation.20 cl, 4 dwgИзобретение относится к медицинской технике, а именно к системам диагностической визуализации ультразвуком. Способ заключается во введении средства усиления контрастности в отслеживаемую ткань, получении, во время периода действия средства, опорного 3D CEUS объема и информации слежения и изображе