MENDES, ZITA,HENRIQUES, ANTONIO, CARLOS, SILVA,HEGGIE, WILLIAM
申请号：
DK09745198
公开号：
DK2358732T3
申请日:
2009.10.23
申请国别(地区):
DK
年份:
2013
代理人:
摘要：
The present invention relates to methods for synthesizing macrolide compounds which are known to have antibacterial activity, and are useful in the therapy of bacterial infections in mammals. More specifically, the invention relates to methods for synthesizing the macrolide antibiotic, gamithromycin utilizing a novel configuration of catalysts, chemical structures, and/or methods. An embodiment of the present invention may include allowing multiple chemical reactions to proceed without the isolation of chemical intermediates. Thus, multiple reactions may occur in one reaction vessel allowing for a considerable decrease in the cycle-time. The present invention also provides a novel method for inhibiting degradation while isolating a structure of a pharmaceutical composition.
