경북대학교 산학협력단;KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
LEE, IN KYU,이인규,PARK, KEUN GYU,박근규,SEO, HYE YOUNG,서혜영
申请号：
KR1020100091023
公开号：
KR1020120029127A
申请日:
2010.09.16
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition containing a promoting agent for clusterin expression or activation for preventing and treating fatty liver is provided. CONSTITUTION: A composition for preventing and treating fatty liver contains a promoting agent for clusterin expression or activation. The fatty liver is a non-alcoholic fatty liver. The promoting agent is a nucleic acid encoding clusterin. The nucleic acid is a recombinant vector containing a nucleic acid encoding clusterin. The vector is an adenovirus vector. 본 발명은 클러스터린 발현 또는 활성 촉진제를 포함하는 지방간 예방 및 치료용 조성물에 관한 것으로, 클러스터린은 간에서 SREBP-1c의 발현을 감소시켜 지방간을 예방 및 치료할 수 있다.
