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Increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages
专利权人:
Panida Vayumhasuwan;Pichit Suvanprakorn;Nardo Zaias
发明人:
Pichit Suvanprakorn,Panida Vayumhasuwan,Nardo Zaias
申请号:
US13252796
公开号:
US08853280B2
申请日:
2011.10.04
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides compositions comprising allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages. In some embodiments a positive charge and enhancers are used in the compositions to allow for increased penetration of the active ingredient through skin and skin appendages. In some embodiments the positively charged active ingredients are either dissolved in the vehicle directly or dissolved in a plurality of beads suspended in the vehicle. The present invention also provides methods for making compositions comprising an allylamine drug compound, and methods of using such compositions for the treatment of fungal infections of the skin and skin appendages.
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