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5-Amino-4-hydroxypentoyl amides.
专利权人:
JANSSEN R & D;MEDIVIR AB
发明人:
KESTELEYN BART RUDOLF ROMANIE,PARKES KELVIN,SAMUELSSON BENGT BERTIL
申请号:
AP2012006228
公开号:
AP2012006228A0
申请日:
2010.12.10
申请国别(地区):
AP
年份:
2012
代理人:
摘要:
HIV inhibitors of formula (I) wherein R1 is halo, C1-4 alkoxy, trifluoromethoxy; R2 is a group of formula (A); R3 is a group of formula (B); R4 is a group of formula (C); n is 0 or 1; A is CH or N; R5 and R6 are hydrogen, C1-4 alkyl, halo; R7 and R8 are C1-4 allyl or C1-4 alkoxy-C1-4 alkyl; R9 is C1-4 allyl, cyclopropyl, trifluoromethyl, C1-4 alkoxy, or dimethylamino; R10 is hydrogen, C1-4 alkyl, cyclopropyl, trifluoromethyl, C1-4 alkoxy, or dimethylamino; pharmaceutically acceptable addition salts and solvates thereof; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds.
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