ANTICORPS MONOCLONAL (AD5-10) CONTRE LE RECEPTEUR DR5 DU LIGAND INDUCTEUR DE L'APOPTOSE LIEE AU FACTEUR DE NECROSE TUMORALE, PROCEDE DE PRODUCTION ET UTILISATIONS DE CELUI-CI
INSTITUTE OF BASIC MEDICAL SCIENCES OF CHINESE ACADEMY OF MEDICAL SCIENCES
发明人:
申请号：
EP05714802.5
公开号：
EP1790663B1
申请日:
2005.03.07
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The present invention discloses a monoclonal antibody against the extracellular domain of human tumor necrosis factor-related apoptosis-inducing ligand receptor DR5 (death receptor 5), The present invention also provides a method of producing the monoclonal antibody, amino acid sequences of the variable regions of the monoclonal antibody's heavy chain and light chain, as well as use of the monoclonal antibody for preparation of a medicament in the treatment of various cancers and /or AIDS.
