Colin William POUTON,Kha Tu Joan HO,Paul James WHITE,Catherine Thoa BUI,Nabila AKHTAR,Hareth Ali AL-WASSITI
申请号：
US16622136
公开号：
US20200246487A1
申请日:
2018.06.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Non-viral nucleic acid delivery agents and methods for the delivery or transfer of nucleic acid molecules to target cells are disclosed. The agents comprise a complex of a nucleic acid cargo for delivery, one or more lipopeptide compound, and one or more polymeric charge-neutralising agent, and the complex is in the form of a particle with substantially neutral or negative surface charge. The agents and methods may be useful in a variety of applications such as therapies (including gene therapies and nucleic acid vaccinations) for diseases and medical disorders.
