Foster, Stephen,Brasel, Kenneth Allan,Mehlin, Christopher,Cerretti, Douglas Pat,Smothers, James F.,Sun, Jilin
申请号:
AU2008288974
公开号:
AU2008288974B2
申请日:
2008.08.19
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Antigen binding proteins that bind to human c-fms protein are provided. Nucleicacids encoding the antigen binding protein, vectors, and cells encoding thesame are also provided. The antigen binding proteins can inhibit binding of c-fmsto CSF-I, reduce monocyte migration into tumors, and reduce the accumulationof tumor-associated macrophages.