A surgical instrument for the dissection of bone and other tissue includes a spindle, a dissection tool and an adaptor disposed between the spindle and the dissection tool. The spindle includes a cavity and a male member projecting into the cavity. The adaptor includes a drive shaft that extends along an axis and includes a first end having a generally cylindrical cross-section and a centrally located aperture partially extending along the axis. The male member is carried by the spindle and extends into the aperture of the dissection tool. The cavity may define a drive portion and a tool receiving aperture. One or more alignment projections may extend from the drive portion into the tool receiving aperture.