Vergnolle, Nathalie,Sallenave, Jean-Michel,Langella, Philippe,Bermudez-Humaran, Luis
申请号：
AU2011206532
公开号：
AU2011206532A1
申请日:
2011.01.14
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention relates to the general field of therapy of Inflammatory Bowel Disease (IBD) and/or Irritable Bowel Syndrome (IBS). Thus, the invention relates to a molecule selected from the trappin-2 protein or an active fraction of the trappin-2 protein, a member of the WAP family proteins or an active fraction of a member of the WAP family proteins or a member of the Serpin family proteins or an active fraction of a member of the Serpin family proteins for the treatment of Irritable Bowel Syndrome (IBS). The invention also relates to a recombinant food-grade bacterium comprising a gene selected from a gene coding for the trappin-2 protein or an active fraction of the trappin-2 protein, a gene coding for a member of the WAP family proteins or an active fraction of a member of the WAP family proteins, or a gene coding for a member of the serpin family proteins or an active fraction of a member of the serpin family proteins.
