KUO, MEI CHUN,郭玫君,DING, HSIOU YU,丁秀玉,WU, MING JIUAN,吴明娟,吳明娟,ZHANG, JI LONG,张继隆,張繼隆,CHIOU, ZAN WEI,邱赞玮,邱贊瑋,CHENG, LING LI,郑玲莉,鄭玲莉
申请号：
TW107132820
公开号：
TWI679017B
申请日:
2018.09.18
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention relates to a use of a plant extract for manufacturing compositions to inhibit Candida albicansbiofilm formation by applying the plant extract to a subject needed. The plant extract comprises at least two of a Rheum officinaleextract, a Scutellariabarbataextract and a Schizonepetatenuifoliaextract and must comprises the Rheum officinaleextract. The Rheum officinaleextract, the Scutellariabarbataextract and the Schizonepetatenuifoliaextract are extracted from 95% ethanol. Accordingly, the plant extract of the present invention comprises at least two plant extracts having synergistic effects which can efficiently inhibit Candida albicansbiofilm formation.本發明有關於一種植物萃取物用於製備抑制白色念珠菌生物膜組成物之用途，係將一有效劑量之植物萃取物投予至一所需個體，以抑制白色念珠菌生物膜之形成；其中植物萃取物包含一大黃( Rheum officinale)萃取物、一本半枝蓮( Scutellariabarbata)萃取物與一杭荊芥( Schizonepetatenuifolia)萃取物其中之二者，且必包含大黃萃取物；大黃萃取物係為大黃95%乙醇萃取物，該本半枝蓮萃取物為本半枝蓮95%乙醇萃取物，且該杭荊芥萃取物為杭荊95%乙醇萃取物；藉此，本發明含有至少兩種植物萃取物之組成物，具有協同作用，能有效抑制白色念珠菌生物膜形成。
