The present disclosure describes ultrasound imaging systems and methods that may be used to assist clinicians in locating lesions during an ultrasound exam that were previously located from images acquired by another imaging system, for example, a magnetic resonance imaging system. A lesion location interface is disclosed that provides visual indications of predicted lesion locations on a display. The predicted lesion locations may be determined by a deformation model included in an ultrasound imaging system as disclosed herein.