UNIVERSITY OF KANSAS;UNIVERSITY OF CONNECTICUT;STOWERS INSTITUTE FOR MEDICAL RESEARCH
发明人:
LI, LINHENG,LU, XIULING,PERRY, JOHN M.,SITTAMPALAM, GURUSINGHAM SITTA,ROY, ANURADHA,HE, XI C.,KASI, RAJESWARI
申请号:
CA2993970
公开号:
CA2993970A1
申请日:
2016.07.28
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The disclosure provides methods of treating cancer by selectively inhibiting p-S552-ß- catenin, p-T217-ß-catenin, p-T332-ß-catenin, and/or p-S675-ß-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.