A personal vaporizing unit (PVU) generates a vapor that is inhaled by a user. A substance (e.g. liquid) in a cartridge is vaporized or atomized by a heating element that heats the liquid. When the PVU is activated, and the user provides suction, the liquid to be vaporized is drawn out of the cartridge, through a wick, and is atomized by the wick into a cavity containing the heating element. The cartridge may be removable and utilize different connectors for connecting with the PVU. A seal may be used for the liquid reservoir that can be punctured upon usage.