Hongzhe Sun,Chi-Fung Godfrey Chan,Shing Chan,Runming Wang
申请号：
US15210019
公开号：
US20170014448A1
申请日:
2016.07.14
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present disclosure relates to methods of using cisplatin active agents in which reduced organ toxicity is observed are provided. In the subject methods, an effective amount is administrated to the host before administration of an effective amount of cisplatin active agents. The cisplatin toxicity reducing agent comprising of stable bismuth(III) complexes or pharmaceutically acceptable salts reduces the levels of undesired toxicity of cisplatin active agents without compromising their anticancer activity. Also provided are methods for use in practicing the subject methods in the treatment of different disease conditions.
