SUN WEILIN,TALDONE TONY,PATEL PALLAV,CHIOSIS GABRIELA
申请号:
IN8297/CHENP/2013
公开号:
IN2013CN08297A
申请日:
2013.10.14
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
123242124131The disclosure relates to Compounds of Formulae (IA) and (IB) and pharmaceutically acceptable salts thereof wherein Z Z Z Xa Xb Xc Xd Y X and X are as defined herein compositions comprising an effective amount of a Compound of Formula (IA) and/or (IB) and methods to treat or prevent a condition such cancer which overexpresses Her kinases comprising administering to an patient in need thereof a therapeutically effective amount of a Compound of Formula (IA) or (IB). The disclosure further relates to compounds of Formulae (IA) and (IB) in which X is a leaving for introducing a radiolabeled atom such as I or I and to methods of using such compounds in the preparation of radiolabeled compounds particularly for use in imaging.