The present invention relates to a device (20) for applying an interface dressing, including an interface dressing (22) which includes a first contact surface (24) and a second contact surface (28), the first contact surface (24) being suitable for being applied in contact with the skin or with a wound of a patient, a pealable application tab (32, 54) of the interface dressing (22), the application tab (32, 54) being arranged against the second contact surface (28), a portion (34, 6) for gripping the application tab (32), extending beyond the second contact surface (28), and a first pealable protector (26) and second pealable protector (30) arranged against the first contact surface (24) and against the second contact surface (28), respectively, the second protector (30) being pealable independently of the application tab (32). The invention also relates to a method for applying such an interface dressing on a patient.