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NOVEL FGFR3 FUSION
专利权人:
ASTELLAS PHARMA INC.
发明人:
SUZUKI ATSUSHI,ASAUMI MAKOTO,TSUNOYAMA KAZUHISA,NISHIMURA KOUICHI,MORINAKA AKIFUMI,YAMAUCHI TOMOHIRO,YOSHINO MASAYASU,YOSHIZAKI HIROAKI
申请号:
PH12014501918
公开号:
PH12014501918A1
申请日:
2014.08.26
申请国别(地区):
PH
年份:
2014
代理人:
摘要:
The purpose of the present invention is to elucidate a polynucleotide which is a new cancer-causing gene, and to thereby provide: a method for detecting the polynucleotide or a polypeptide encoded by the polynucleotide a kit for detection a probe set and a primer set. Another purpose is to provide a pharmaceutical composition for treating cancer. This detection method detects a fusion gene that comprises a part of the FGFR3 gene and a part of the TACC3 gene, or a fusion protein encoded by the fusion gene. Said primer set, probe set, and kit for detection each contains a sense primer and a probe set which are designed from the part that encodes FGFR3 and an antisense primer and a probe set which are designed from the part that encodes TACC3. A cancer-treating pharmaceutical composition that is positive to said fusion gene or positive to said polypeptide is provided, because an inhibitor of said polypeptide exhibits an antitumor effect.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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