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NONSTEROIDAL IMMUNOMODULATING KIT AND COMPOSITION AND USES THEREOF
专利权人:
Foamix Pharmaceuticals Ltd.
发明人:
Dov Tamarkin,Meir Eini,Doron Friedman
申请号:
US16216575
公开号:
US20190307685A1
申请日:
2018.12.11
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A composition and therapeutic kit including an aerosol packaging assembly including a container accommodating a pressurized product and an outlet capable of releasing a foamable composition, including a nonsteroidal immunomodulating agent as a foam. The pressurized product includes a foamable composition including:a) a container accommodating a pressurized product; andb) an outlet capable of releasing the pressurized product as a foam; wherein the pressurized product comprises a foamable composition including: i. a nonsteroidal immunomodulating agent;ii. at least one organic carrier selected from the group consisting of a hydrophobic organic carrier, a polar solvent, an emollient and mixtures thereof, at a concentration of about 2% to about 50% by weight;iii. a surface-active agent;iv. about 0.1% to about 5% by weight of a therapeutically active foam adjuvant, selected from the group consisting of a fatty alcohol, a fatty acid, a hydroxyl fatty acid; and mixtures thereof;v. about 0.01% to about 5% by weight of at least one polymeric additive selected from the group consisting of a bioadhesive agent, a gelling agent, a film forming agent and a phase change agent;vi. water; andvii. liquefied or compressed gas propellant at a concentration of about 3% to about 25% by weight of the total composition.
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