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Suicidal LSD1 inhibitors targeting SOX2-expressing cancer cells
专利权人:
发明人:
Hui Zhang
申请号:
US14894893
公开号:
US09918983B2
申请日:
2014.05.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Disclosed are inhibitors of lysine-specific demethylase I (LSD1) synthetic methods for making the compounds pharmaceutical compositions comprising the compounds and methods of treating cancers characterized by the presence of Sox2 using the compounds and compositions Also disclosed are methods of treating cancers characterized by the presence of Sox2 using inhibitors of LSD1 and/or histone deacetylation I (HDAC1). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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