MITOCHONDRIA-TARGETING PLATINUM(IV) PRODRUG

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专利权人:

University of Georgia Research Foundation; Inc.

发明人:

DHAR, Shanta,PATHAK, Rakesh,MARRACHE, Sean

申请号：

EP15776882

公开号：

EP3129017A4

申请日:

2015.04.08

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Pt(IV) compounds include a mitochondria targeting moiety. One example of a Pt(IV) compound having a mitochondria targeting moiety is a Pt(IV) cisplatin-based compound. Upon reduction, the mitochondrial targeting moieties are released resulting in a Pt(II) therapeutic agent. Pt(IV) compounds including a mitochondria targeting moiety can be included in nanoparticles. The compounds or nanoparticles can be used to treat, for example, cancer.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/