Pharmaceutical preparation containing an antivirally active dihydroquinazoline derivative

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专利权人:

AICURIS GMBH & CO. KG

发明人:

GRUNDER DOMINIQUE,VAN HOOGEVEST PETER,PAULUS KERSTIN,SCHWAB WILFRIED

申请号：

NZ62844413

公开号：

NZ628444A

申请日:

2013.02.28

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Provided are intravenous pharmaceutical compositions comprising the antiviral agent { 8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-3,4-dihydroquinazolin-4-yl} acetic acid (letermovir) and at least one excipient selected from the cyclodextrins, lysine, and arginine. The inclusion of at least one of a cyclodextrin, lysine, and arginine is to stabilise the active pharmaceutical ingredient.

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