P38 kinase inhibitors

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专利权人:

Matthew Clark

发明人:

Matthew Clark

申请号：

US12375184

公开号：

US08119798B2

申请日:

2007.08.01

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Compounds of formula (I) and (II) are disclosed, as well as methods for their identification, their preparation, pharmaceutical compositions containing them, and their use in treating disease. The compounds inhibit the production of TNF-alpha and interleukins (IL) by the inhibition of p38 kinase. They are useful in the treatment of inflammation and arthritis.

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