HILLE THOMAS,HORSTMANN MICHAEL,MULLER WALTER,Hille Thomas,Horstmann Michael,Muller Walter
申请号:
SI200731679
公开号:
SI2769714T1
申请日:
2007.11.07
申请国别(地区):
SI
年份:
2015
代理人:
摘要:
The therapeutic system has an active substance impermeable rear layer (1), a detention adhesive, and a matrix layer (2) containing an active substance buprenorphine and carboxylic acid i.e. levulinic acid, and a detachable protection layer (3). The matrix layer is formed on the basis of amine-resistant dimethyl polysiloxane or polyisobutylene, where the matrix layer dissolves the buprenorphine in the carboxylic acid. A solution in a form of droplets is dispersed in the matrix layer, which stays in diffusible contact with a polyacrylate layer.