An apparatus for delivery of a substance to an anatomical region in a body can include a catheter comprising a catheter body, and one or more electrically conductive elements supported by the catheter body and in electrical communication with one or more sources of electrical stimulus. The catheter body can comprise a lumen therein, a substantially closed distal end, and an infusion section configured to permit fluid to pass through the catheter body and that can have a length that is less than or equal to the length of the catheter body. In some embodiments, the apparatus can comprise a coiled member positioned within the lumen of the catheter body. The coiled member can comprise adjacent coils and can permit the uniform flow of the substance through one or more holes formed in the catheter body.