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RISPERIDONE-CONTAINING MICROCAPSULE, METHOD FOR PREPARING SAME AND RELEASE CONTROL METHOD
专利权人:
NIPRO CORPORATION
发明人:
Naoya KOSAKA,Naoyuki MIYANAGA,Minoru HATSUSHIKA
申请号:
US16881277
公开号:
US20200281863A1
申请日:
2020.05.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A microcapsule contains a biodegradable polymer and risperidone and has a sustained release property. The biodegradable polymer contained in the microcapsule has a molecular weight corresponding to 85% or more of an initial molecular weight (Mw) of the biodegradable polymer. A method of producing the microcapsule is also disclosed. The method of producing a microcapsule has (A) a step of preparing a first phase by mixing a solution of a biodegradable polymer and a solution of risperidone which are prepared separately, (B) a step of, immediately after the preparation of the first phase, mixing the first phase with a second phase being an aqueous phase to prepare an emulsion, and (C) a step of subjecting the resulting emulsion to in-water drying.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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