Cammue, Bruno,Carron, Delphine,Cassiman, David,De Coninck, Barbara,Mathys, Janick,Spincemaille, Pieter,Thevissen, Karin
申请号:
AU2011340812
公开号:
AU2011340812A1
申请日:
2011.12.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to methods and materials able to confer an increased tolerance or resistance to oxidative stress in cells or organisms. In particular, the present invention provides peptides possessing pharmacological or biotherapeutic activity and nucleic acids encoding said peptides which can be used to improve the tolerance of a microbial or eukaryotic cell to oxidative stress, to confer oxidative stress tolerance to an organism when transfected herein, or for the treatment and the prophylaxis of a wide range of oxidative stress-related pathologies in mammals, including humans, particularly mitochondrial dysfunction related disorders.