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Capsule formulation comprising fexofenadine
专利权人:
LLC;R.P. Scherer Technologies
发明人:
Shelley, Rickey S.
申请号:
AU2014284294
公开号:
AU2014284294A1
申请日:
2014.07.03
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention relates to a composition for use as a capsule fill comprising (a) fexofenadine hydrohalide; (b) alkali hydroxide, wherein the molar ratio of the alkali hydroxide to fexofenadine is greater than 1.5:1; (c) a solvent, and optionally a solubilizer. This composition is a stable solution, and comprises a sufficiently high concentration of fexofenadine to be useful for manufacture of capsules comprising a pharmaceutically efficacious amount of the fexofenadine for treatment of the symptoms of allergies, hay fever, or urticarial. Further, the present invention relates to a capsule comprising such a fill.
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