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BURST TYPE LAGGED-RELEASE CONTROLLED COMPOSITION AND PREPARATION METHOD THEREOF
专利权人:
发明人:
박해준,김동호,최진수,김화정
申请号:
KR1020120010613
公开号:
KR1013840550000B1
申请日:
2012.02.02
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
PURPOSE: A burst type delay emission controlling composition is provided to emit a biological active component in the composition when a rainy season sets in whereby a biological active component can applied at an appropriate period. CONSTITUTION: A burst type delay emission controlling composition which as an initial emission delay characteristic includes a center part which has a water-expandable polymer and biological active components in the water-expandable polymer; and a peripheral part which is formed on the surface of the center part to surround the center part and is water-permeable. A manufacturing method of the delay emission controlling composition includes a step of adding acids into the water-expandable polymer to control the pH of the water-expandable polymer to 5.0-6.0, mixing the water-expandable polymer with a microbial cell, and freezing and drying the mixture to prepare the center part; and a step of spraying magnesium sulfate onto the center part and drying the same and spraying a peripheral part-forming solution to form the peripheral part. [Reference numerals] (AA) Dispersing; (BB) Moisture injection; (CC) Periphery; (DD) Biological vital component; (EE) Water swelling polymer살포 초기에는 활성 물질의 방출이 없거나 미미하다가 특정 환경이 도래하면 활성 물질의 방출이 이루어지는 지연 방출 제어 조성물로서, 수팽창성 고분자 중합체 및 상기 수팽창성 고분자 중합체 내에 포함되어 있는 생물학적 활성 성분을 포함하는 중심부; 및 상기 중심부를 감싸도록 상기 중심부의 표면에 형성되어 있고 투수성이 있는 주변부를 포함하는, 초기 방출억제 특성을 갖는 버스트(burst)형 지연 방출 제어 조성물을 제공한다.
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中国工程科技知识中心
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