The invention relates to an applicator device, comprising an applicator element (9) for applying a substance (27) present in a substance chamber (25, 27) to a skin section. The applicator device (1) comprises an applicator part (2) having an upper housing part (8) and a vibration part (3) having a lower housing part (4), wherein in the lower housing part (4) a vibration element (10) is provided which can be actuated by a power source (6) and the vibrations of which can be transmitted to the upper housing part (8) and the applicator element (9), and wherein an activator device (22) for generating heating or cooling energy is provided in the upper housing part (8), wherein the heating or cooling energy can be transferred to the substance (27) present in the substance chamber (25, 27).