Methods for increasing the stabilization of hypoxia inducible factor-1 alpha

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专利权人:

Aerpio Therapeutics Inc.

发明人:

Shalwitz, Robert,Gardner, Joseph H.

申请号：

AU2010314973

公开号：

AU2010314973A1

申请日:

2010.11.05

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

Disclosed herein are methods for controlling the activity of hypoxia- inducible transcription factor 1 -alpha (HIF- lα) and diseases, conditions, or syndromes related thereto, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia. Further disclosed are pharmaceutical compositions comprising HIF- lα prolyl hydroxylase inhibitors useful in treating diseases, conditions, and/or syndromes related thereto the activity of HIF-I α.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/